Cambridge (CIE) IGCSE Biology

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(Mitosis)

Mitosis

Mitosis - The Cell's Copy Machine (Extended)

 

What Is Mitosis?

Mitosis is a type of cell division where one parent cell splits into two genetically identical daughter cells. It ensures that each new cell has the same number of chromosomes as the original cell.

Think of mitosis like photocopying a document – the two new cells (copies) are identical to the original

 

Key Features of Mitosis

FeatureExplanation
Genetically Identical CellsDaughter cells are exact copies of the parent cell (same DNA).
Chromosome NumberThe number of chromosomes stays the same in the new cells.
PurposeUsed for growth, repair, replacement of cells, and asexual reproduction.

 

Steps in Mitosis

Although details of the stages aren't required, here's a simple summary to understand the process:

  1. Replication of Chromosomes

    • Before mitosis starts, the chromosomes in the cell replicate, creating identical copies (called sister chromatids).

    • Analogy: Imagine copying a stack of pages. You’ll now have two identical stacks!

  2. Chromosome Separation

    • During mitosis, the sister chromatids first line up along the center to be split.

    • The cell then separates and the chromosomes are pulled to opposite sides of the cell.

    • Analogy: Think of tearing the stack of pages in half to distribute them equally.

  3. Two Identical Cells

    • The cell divides into two daughter cells, each with the same number and type of chromosomes as the parent cell.

 

mitosis - splitting of cell into two daughter cells

 

Why Is Mitosis Important?

FunctionExplanation
GrowthHelps multicellular organisms grow by adding more cells.
RepairReplaces damaged cells (e.g., healing a cut).
ReplacementReplaces old or worn-out cells (e.g., skin cells).
Asexual ReproductionUsed by some organisms (like bacteria) to reproduce without needing a mate.

 

Stem Cells and Mitosis

  • Stem cells are unspecialised cells that divide by mitosis.
  • These cells can then specialise into different types of cells (e.g., muscle cells, nerve cells).
TermDefinition
UnspecialisedNot yet assigned a specific function.
SpecialisedHave a specific function (e.g., skin cell for protection).

 

Key Facts to Remember

  • Exact Replication of Chromosomes:
    Before mitosis, chromosomes replicate to ensure the daughter cells have the same genetic material.

  • Maintaining Chromosome Number:
    Mitosis keeps the chromosome number constant, ensuring no loss or duplication.

    Example in humans:

    • Parent cell has 46 chromosomes.
    • After mitosis, each daughter cell also has 46 chromosomes.

 

 

 

Tuity Tip

Hover me!

Mitosis is about making copies, so everything stays the same (identical cells).

It’s for growth, repair, and asexual reproduction – not making gametes (that's meiosis).

Remember, stem cells divide by mitosis to create new, useful cells.

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